Cushing's syndrome is a disorder characterized by the body's prolonged production of excess cortisol hormone. This research involved patients diagnosed with Cushing's syndrome who were in remission after treatment, aiming to investigate at a biological level why psychological symptoms persist even after cortisol levels returned to normal with treatment.
Research has shown that even with treatment, Cushing's Syndrome leaves a lasting "hormonal memory" in the body. Even when patients' cortisol levels return completely to normal with treatment, the past excessive hormonal load leaves permanent genetic traces in the body's cells. This has paved the way for research into epigenetically targeted approaches and neurosteroid-based interventions as adjunctive treatments for the psychological morbidity associated with Cushing's disease.
We congratulate our researcher for their contributions to the literature and wish them continued success.
You can access the article of the study, in which Research Assistant Sevim EYÜPOĞLU was part of the research team, through the relevant links below.
